SkinMedica Retinol Complex 1.0 white pump bottle for anti-aging skincare.

SkinMedica Retinol Complex skincare bottles with anti-aging and skin renewal benefits listed.

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SkinMedica Retinol Complex 1.0 silver bottle beside text listing benefits of glass packaging.

Three SkinMedica Retinol Complex bottles in 0.25, 0.5, and 1.0 strengths on a light background

Before and after photos of a 59-year-old female's skin after 12 weeks of Retinol Complex 1.0.

Retinol clinical study before and after photos of a 45-year-old woman, week 12.

SkinMedica Retinol Complex 1.0 serum bottle and packaging on a white background

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SkinMedica Retinol Complex 1.0%

Name: SkinMedica Retinol Complex 1.0%
SKU: 300234926016
Price: 96.0 USD
Availability: InStock

$96.00

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Offer valid September 1–30, 2026, while supplies last.

SkinMedica Retinol Complex 1.0%

The highest concentration in the SkinMedica retinol range, formulated for experienced retinol users ready for maximum renewal results. Retinol Complex 1.0% delivers powerful anti-aging benefits — visibly diminishing fine lines and coarse wrinkles and enhancing skin tone, texture, and resiliency — while the PhytoShield™ Complex antioxidant blend helps maintain tolerability even at this advanced strength.

KEY BENEFITS

Renews skin and diminishes the appearance of fine lines and coarse wrinkles
Enhances skin tone, texture, and resiliency
PhytoShield™ Complex minimizes irritation while boosting antioxidant protection
Highest concentration in the SkinMedica retinol range for maximum renewal

WHO IT’S FOR

Experienced retinol users whose skin has been pre-conditioned to tolerate higher concentrations. Not recommended as a starting point — build up gradually using 0.25% and 0.5% first.

RETINOL PROGRESSION

SkinMedica offers a complete retinol range — 0.25% (beginner) → 0.5% (intermediate) → 1.0% (advanced) — designed to help you gradually build retinol tolerance over time.

HOW TO USE

Apply a pea-sized amount to clean, dry skin in the evening. Begin with 2–3 times per week and gradually increase frequency as tolerated. Always follow with broad-spectrum SPF in the morning.

Application

How to use

When to Apply Apply In the evening after cleansing and toning and before applying your moisturizer. If a retinol product has never been used before, begin twice a week 2-3 days apart, gradually increasing frequency to every other night, and then advancing to each evening or as tolerated.
Where to Apply Apply to entire face. Avoid getting in eyes. If contact occurs, rinse eyes thoroughly with water.
Caution Do not use if you are pregnant, lactating or planning to become pregnant. Mild redness, peeling and irritation are expected when using this product. Use a daily sun protection with SPF 30 or higher and limit sun exposure while using this product and for a week following discontinuation.

Ingredients

Aqua/Water/Eau, Cetyl Ethylhexanoate, Glycine Soja (Soybean) Oil, Caprylic/Capric Triglyceride, Glycerin, Niacinamide, Polyacrylate-13, Squalane, Polysorbate 20, Retinol, Palmitoyl Tripeptide-8, Dunaliella Salina Extract, Magnolia Grandiflora Bark Extract, Tocopherol, Tocotrienols, Ceramide NP, Bisabolol, Tocopheryl Acetate, Oryza Sativa (Rice) Bran Oil, Butylene Glycol, Cetyl Palmitate, Laureth-23, Trideceth-6 Phosphate, Sodium Hydroxide, Dicaprylyl Ether, Lauryl Alcohol, Polyisobutene, Dextran, Potassium Sorbate, Disodium EDTA, Phenoxyethanol, Ethylhexylglycerin